Hi Stephen,
If there are not too many locations and you are not an experienced coder or programmer, running the simulations by hand may be the quickest approach.
The other approach would be to use parametric simulations: You would first download a weather file for each location and put them in a folder, and then use the method described for parametric simulations here:
sam.nrel.gov/simulation-options.html. That would require exporting the 8760 data for each run from the parametric table by hand.
You could also use the solar-resource-simulate-multiple-files.lk script available here:
github.com/NREL/SAM/tree/develop/samples/LK%20Scripts%20for%20SAM (instructions are at the bottom of that page for how to download and run LK scripts).
Best regards,
Paul.